Liquid Mobile Hair Loss and Regrowth Program 

When a topical hair regrowth product is applied to the scalp, it is used to stimulate hair growth in adult men and women with a certain type of baldness and hair loss, from very mild, mild, moderate to severe. If hair growth is going to occur with the use of a product, it usually occurs after the medicine has been used for several months and lasts only as long as the medicine continues to be used. Hair loss will begin again within a few months after treatment is stopped.

 

Hair Loss – “Androgenic Alopecia”
Male and Female Pattern Baldness, also known as “Androgenic Alopecia”, is the most common cause of hair loss and will affect up to 70% of men and 40% of women at some point in their lifetime. Men typically present with hairline recession at the temples and hair loss on the upper surface of the head, also known as vertex balding. Women typically present diffuse, or scattered, thinning of the hair over the top of their scalps. People who suffer from this type of hair loss have an underlying sensitivity to “hair follicle miniaturization” due to androgenic hormones.

Hair Loss Patterns from Mild to Severe

Causes of Hair Loss
There are many causes of hair loss. Causes include certain diseases, chemical exposure, or drug use. The most common causes are:

• Androgenic Alopecia (AGA) – More than 95% of hair loss in men is due to this condition. Women can also be affected by this common type of hair loss.
• Poor Nutrition – Usually complete baldness is not seen in people with nutritional deficiencies, thinning of the hair is more common. Studies show that limited food intake and deficiencies in certain nutrients can cause thinning. These include deficiencies of biotin, amino acids (protein), zinc, and iron. Consuming a diet high in animal fat, such as fast food, can also have a negative effect on hair loss.
• Stress – Stress has been shown to restrict the blood supply to capillaries which prevents oxygen and nutrients from reaching the hair follicle which can prevent hair growth. This effect is similar to having poor circulation.
• Medications – Some medications can cause hair loss, especially medications that affect hormone levels. These medications include contraceptive pills, some forms of hormone replacement therapy, anabolic steroids, and acne medication. Other medications that can have an effect on hair loss include those for blood pressure, diabetes, heart disease, and cholesterol.

 

FDA Approved Treatments for Hair Loss
There are currently two treatments approved by the FDA for treatment of miniaturization of hair-follicles from AGA.

• Finasteride (Propecia®)– The American Hair Loss Association notes finasteride is a prescription oral treatment for male pattern baldness. It reportedly reduces the active levels of DHT in your body to prevent miniaturization of hair follicles. Women should not take oral finasteride due to its risks. In addition, many men who are prescribed finasteride to be taken orally by tablet experience significant side effects which may reduce quality of life. These side effects may include loss of libido, erectile dysfunction, hypogonadism, gynecomastia, and sexual dysfunction.
• Minoxidil (Rogaine®)– An over the counter topical treatment that has been used since the 1990’s to treat baldness in men and women. It reportedly promotes new hair growth by increasing cutaneous blood flow to shrinking hair follicles. This may cause follicles in the telogen phase to shed, which are then replaced by thicker hairs in a new anagen phase. It is generally recognized as safe and can be effective by itself if used during the early onset of alopecia.

 

Compounded Hair Loss Solutions
Other medications are can be effective for the treatment of alopecia when applied directly to the scalp. Pharmacies offer compounded formulas that combine FDA approved medications and alternative therapies creating a custom product that may treat, prevent, and reverse hair thinning and loss. Common compounded ingredients include:

• Ketoconazole – Ketoconazole, an anti-fungal medication, can also be effective in stimulating new hair growth for sufferers of AGA. DHT is the hormone responsible for shrinking hair follicles in people who have this condition. In addition to killing fungi, ketoconazole is also helpful in countering the effects of DHT.
• Minoxidil fortified with Finasteride– Finasteride acts by reducing DHT levels, thereby inhibiting miniaturization of hair follicles in patients with AGA. Oral finasteride may be associated with side effects such as decreased libido, sexual dysfunction, and gynecomastia. Scalp-applied topical finasteride can be considered for hair density maintenance after initial improvement with oral finasteride, thereby obviating the indefinite use of oral finasteride. Topical finasteride may absorb less systemically than oral finasteride, therefore reducing the side effects associated with oral finasteride.
• Latanoprost – A double-blind scientific study published in the May 2012 issue of the Journal of the American Academy of Dermatology has found that latanoprost, a drug that mimics naturally-derived compound molecules called prostaglandins, significantly increases hair density on the scalp after 24 weeks of treatment in young men with mild hair loss. Latanoprost, like the eyelash restoration drug bimatoprost (better-known by its brand name Latisse), has been used to treat glaucoma. And like bimatoprost, latanoprost has been used to treat eyelash alopecia. The scientists who conducted the study sought to determine if latanoprost could stimulate hair growth when applied topically on the scalp.^[1]
• Azelaic Acid– A naturally occurring substance found in whole grains that contains a mild antibiotic designed to reduce harmful bacteria from the skin. It is also said to be a potential inhibitor of 5-alpha-reductase in human skin. A reduction of this enzyme reduces the amount DHT in the body and therefore can have a similar effect to finasteride; the active ingredient in the FDA approved oral hair loss solution Propecia.
• Dutasteride – Traditionally, dutasteride may assist with benign prostatic hyperplasia. However, it may also assist with male pattern hair loss.
• Tretinoin- Commonly, topical tretinoin may be associated with the potential to help acne or aging skin.^[3]When combined with minoxidil, studies have suggested tretinoin may also help stimulate hair growth.
• Ketoconazole – Most commonly, ketoconazole is considered for the potential to assist with fungal infections. However, some studies have suggested that topical ketoconazole may also assist with male pattern hair loss
• GHK-CU – Copper has been studied for centuries for its notable benefits for the body and its anti-oxidant properties¹. Recently, interest surrounding GHK-Cu or copper peptides has steadily grown. Since 2015, Google has noted a trend in copper peptide searches, with an upward trendstarting in 2022. Another report suggests that from 2023 until mid 2024, the monthly volume for the search term “copper peptide serum” has grown about 68%. Notably, ingredients matter to consumers when it comes to skincare since 43% of consumers consider it an important factor when purchasing skincare products.
• Biotin – A dietary component that is important for the metabolism of carbohydrates, fats, and amino acids. It is found primarily in liver, kidney, and muscle. Biotin functions as an essential cofactor for five carboxylases that catalyze steps in fatty acid, glucose, and amino acid metabolism. It is also an important factor in histone modifications, gene regulation, and cell signaling. Biotin has been promoted to be useful in the treatment of hair and nail problems, cradle cap (seborrheic dermatitis).
• Sildenafil (Viagra) – A vasoactive agent that is commonly prescribed to treat erectile dysfunction (impotence) in men, and to reduce symptoms in patients with pulmonary arterial hypertension (PAH). By decreasing vascular resistance and relaxing muscles, sildenafil increases blood flow to particular areas of the body including the penis. Sildenafil is generally taken 30 to 60 minutes prior to sexual intercourse, sildenafil troche may be taken up to 10 minutes before intercourse.
• Tadalafil – A selective phosphodiesterase (PDE) type 5 inhibitor similar to sildenafil and vardenafil. It is administered orally for the treatment of male erectile dysfunction (ED), pulmonary arterial hypertension (PAH), benign prostatic hypertrophy (BPH), or the concurrent treatment of erectile dysfunction and BPH. Tadalafil does not inhibit prostaglandins as do some agents for treating impotence (e.g., alprostadil). Unlike sildenafil, visual disturbances have not been reported with tadalafil, which is more selective for PDE5 than for PDE6 present in the retina. The duration of action of tadalafil for the treatment of ED (up to 36 hours) appears to be longer than that of sildenafil and vardenafil. Because PDE inhibitors promote erection only in the presence of sexual stimulation, the longer duration of action of tadalafil allows for more spontaneity in sexual activity

 

Before Using Solution
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. It is essential that the Guest works closely with their primary medical team to ensure this is part of their overall health and wellness plan, and that their primary care team does not feel there are any contra-indications. Additionally, the following should be considered:

Ages
Studies have shown that the medicine works best in younger patients who have a short history of hair loss.

Contraindications for Solution

• Breastfeeding: Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding, therefore it is not recommended for anyone that is breastfeeding.
• Skin Sensitivity: A skin problem such as an irritation, or a sunburn on the scalp, may cause too much topical to be absorbed into the body and may increase the chance of side effects.
• Pregnancy: Women that are pregnant, wanting to get pregnant or of child bearing age.

 

Proper Use of Solution
The medicine usually comes with patient instructions. It is important that your Guest reads the instructions carefully. It is very important that you use this medicine only as directed. Do not use more of it and do not use it more often than ordered. To do so may increase the chance of it being absorbed through the skin. For the same reason, do not apply to other parts of your body. Absorption into the body may affect the heart and blood vessels and cause unwanted effects.

Do not use any other skin products on the same skin area on which you use this product. Hair coloring, hair permanents, and hair relaxers may be used during therapy as long as the scalp is washed just before applying the hair coloring, permanent, or relaxer. It should not be used 24 hours before and after the hair treatment procedure. Be sure to not double your doses of to make up for any missed doses.

 

Applying Topical Solution

• Make sure your hair and scalp are completely dry before applying this medicine.
• Apply the amount prescribed to the area of the scalp being treated, beginning in the center of the area. Follow your instructions on how to apply if using an applicator.
• Do not shampoo your hair for 4 hours after applying.
• Immediately after using this medicine, wash your hands to remove any medicine that may be on them.
• Do not use a hairdryer to dry the scalp after you apply solution. Blowing with a hairdryer on the scalp may make the treatment less effective.
• Allow the medicine to completely dry for 2 to 4 hours after applying it, including before going to bed. It can stain clothing, hats, or bed linen if your hair or scalp is not fully dry after using the medicine.
• Avoid transferring the medicine while wet to other parts of the body. This can occur if the medicine gets on your pillowcase or bed linens or if your hands are not washed after applying.

 

Applying Topical Foam

• Open the container by matching the arrow on can ring with the arrow on cap. Pull off the cap.
• Part the hair into one or more rows to expose the hair thinning area on the scalp.
• Hold the can upside down and press the nozzle to put foam on your fingers.
• Use your fingers to spread the foam over the hair loss area and gently massage into your scalp.
• Immediately after using this medicine, wash your hands to remove any medicine that may be on them .
• If your scalp becomes abraded, irritated, or sunburned, check with your clinical team before applying product.

Topical foam or solution is for use on the scalp only. Keep this medicine away from the eyes, nose, and mouth. If you should accidentally get some in your eyes, nose, or mouth, flush the area thoroughly with cool tap water. If you are using the pump spray, be careful not to breathe in the spray. Do not use the foam near heat or open flame, or while smoking. Do not puncture, break, or burn the aerosol can.

 

Dosing
The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For hair growth:
  • For topical solution dosage form:
    • Adults—Apply 1 milliliter (mL) to the scalp daily.
  • For topical foam dosage form:
    • Adults—Apply half a capful to the scalp daily.
  • For Empower Hair Regrowth Products
    • Adults – Apply 1 to 2 drops to the affected area once per day

 

Regrowth Timeline

 

 

 

Compounds, Medications & Therapies

Women of Child Bearing Age Hair Loss
GHK-Cu Scalp Solution (60 mL), 0.5%

Very Mild Hair Loss
Hair Restore Lite Scalp Solution (Minoxidil / Azelaic Acid) (60 mL), 5/12.5%

Mild Hair Loss
Hair Restore Ultra Scalp Solution (Minoxidil / Azelaic Acid / Finasteride / Ketoconazole) (60 mL), 5/12.5/0.1/2%

Moderate Hair Loss
Hair Restore MFK Scalp Solution (Minoxidil / Finasteride / Ketoconazole) (60 mL)  5/0.3/2%

Severe Hair Loss (more than 100 hairs lost per day, large clumps falling out)
Hair Restore MFT Scalp Solution (Minoxidil / Finasteride / Tretinoin) (60 mL) 5/0.3/0/01%

ProCell Micro-needling for Hair Loss
Procell micro-needling is a non-invasive procedure that uses micro-needling to stimulate hair growth. It’s a type of stem cell microneedling that can help with hair loss.

Mild Erectile Dysfuction to be used with Hair Loss and/or HRT
Sildenafil Citrate – 5mg, 10mg, 20mg, 25mg, 50mg, 100mg Troche & Capsules

Moderate Erectile Dysfuction to be used with Hair Loss and/or HRT
Tadalafil – 2.5 mg, 5mg, 10mg, 20mg Troche & Capsules

 

Missed Solution Dose
If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

 

Solution Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Flammable: Keep away from fire or flame.

 

Solution Precautions
It is important that the Guest checks in for regular visits to make sure that this medicine is working properly and to check for unwanted effects. Educate Guest to reach out if they notice continued itching, redness, or burning of your scalp after applied. If the itching, redness, or burning is severe, wash the medicine off and check with the clinical team before using it again. Hair loss may continue for 2 weeks after you start using medicine. Guest should communicate if  hair growth does not increase after using for 4 months.

 

Solution Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your primary care team as soon as possible if any of the following side effects occur:

Less common

• Itching or skin rash (continued)

Rare

• Acne at site of application
• burning of scalp
• facial hair growth
• increased hair loss
• inflammation or soreness at root of hair
• reddened skin
• swelling of face

Signs and symptoms of too much medicine being absorbed into the body—Rare

• Blurred vision or other changes in vision
• chest pain
• dizziness
• fainting
• fast or irregular heartbeat
• flushing
• headache
• lightheadedness
• numbness or tingling of hands, feet, or face
• swelling of face, hands, feet, or lower legs
• weight gain (rapid)

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

 

Sources
Hair Restore Lite Scalp Solution
https://www.empowerpharmacy.com/compounding-pharmacy/hair-restore-lite-scalp-solution/

 Hair Restore Ultra Scalp Solution (Minoxidil / Azelaic Acid / Finasteride / Ketoconazole) (60 mL)
https://www.empowerpharmacy.com/compounding-pharmacy/hair-restore-ultra-scalp-solution/

Hair Restore MFK Scalp Solution (Minoxidil / Finasteride / Ketoconazole) (60 mL)
https://www.empowerpharmacy.com/compounding-pharmacy/hair-restore-mfk-scalp-solution/

Hair Restore MFT Scalp Solution (Minoxidil / Finasteride / Tretinoin) (60 mL)
https://www.empowerpharmacy.com/compounding-pharmacy/hair-restore-mft-scalp-solution/

GHK-Cu Scalp Solution (60 mL)
https://www.empowerpharmacy.com/compounding-pharmacy/ghk-cu-scalp-solution/

Sildenafil
https://www.empowerpharmacy.com/compounding-pharmacy/sildenafil-tablets/

Tadalafil (Cialis)
https://www.empowerpharmacy.com/compounding-pharmacy/tadalafil-tablets/

Additional Suggestions
It is recommended that you work closely with your primary physician and medical team, along with a wellness consultant, fitness trainer and nutritionist, to best round out your wellness journey and to build good habits. For emergencies, immediately dial 911, then contact your primary medical team and Liquid Mobile.